| Host: | Rabbit |
| Applications: | FC/IF/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Nuclear Respiratory Factor 1 is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM2H39 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | NRF1 |
| Gene ID: | 4899 |
| Uniprot ID: | NRF1_HUMAN |
| Post Translational Modifications | Phosphorylation enhances DNA binding. |
| Function | Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
| Protein Name | Nuclear Respiratory Factor 1Nrf-1Alpha Palindromic-Binding ProteinAlpha-Pal |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-2151201 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Respiratory Factor 1 antibodyAnti-Nrf-1 antibodyAnti-Alpha Palindromic-Binding Protein antibodyAnti-Alpha-Pal antibodyAnti-NRF1 antibody |
Information sourced from Uniprot.org
