Anti-Recombinant-NFKBIE antibody [RM1C72] (STJA0022868)

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STJA0022868
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Host: Rabbit
Applications: IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Recombinant-Nf-Kappa-B Inhibitor Epsilon for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : RM1C72
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IP: 1:20
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: NFKBIE
Gene ID: 4794
Uniprot ID: IKBE_HUMAN
Post Translational Modifications Serine phosphorylated.followed by proteasome-dependent degradation.
Function Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity. Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50-c-Rel) complexes. Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development.
Protein Name Nf-Kappa-B Inhibitor Epsilon
Nf-Kappa-Bie
I-Kappa-B-Epsilon
Ikb-E
Ikb-Epsilon
Ikappabepsilon
Database Links Reactome: R-HSA-1169091
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Nf-Kappa-B Inhibitor Epsilon antibody
Anti-Nf-Kappa-Bie antibody
Anti-I-Kappa-B-Epsilon antibody
Anti-Ikb-E antibody
Anti-Ikb-Epsilon antibody
Anti-Ikappabepsilon antibody
Anti-NFKBIE antibody
Anti-IKBE antibody

Information sourced from Uniprot.org