Anti-Recombinant-ITGA9 antibody [RM2F05] (STJA0025474)

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STJA0025474
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Integrin Alpha-9 is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2F05
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ITGA9
Gene ID: 3680
Uniprot ID: ITA9_HUMAN
Function Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion. Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction.
Protein Name Integrin Alpha-9
Integrin Alpha-Rlc
Database Links Reactome: R-HSA-216083
Reactome: R-HSA-3000178
Reactome: R-HSA-445144
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-9 antibody
Anti-Integrin Alpha-Rlc antibody
Anti-ITGA9 antibody

Information sourced from Uniprot.org

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