Host: |
Rabbit |
Applications: |
FC/IF/IHC/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : |
Rabbit monoclonal antibody anti-Recombinant-High Mobility Group Protein Hmg-I/Hmg-Y is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
Clonality : |
Monoclonal |
Clone ID : |
RM1Q25 |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.01M PBS |
Purification: |
Protein A/G purified from cell culture supernatant |
Dilution Range: |
FCM: 1:20-1:100 |
Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Function | HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. |
Protein Name | High Mobility Group Protein Hmg-I/Hmg-YHmg-I(YHigh Mobility Group At-Hook Protein 1High Mobility Group Protein A1High Mobility Group Protein R |
Database Links | Reactome: R-HSA-162592Reactome: R-HSA-164843Reactome: R-HSA-175567Reactome: R-HSA-177539Reactome: R-HSA-180689Reactome: R-HSA-180910Reactome: R-HSA-2559584 |
Cellular Localisation | NucleusChromosome |
Alternative Antibody Names | Anti-High Mobility Group Protein Hmg-I/Hmg-Y antibodyAnti-Hmg-I(Y antibodyAnti-High Mobility Group At-Hook Protein 1 antibodyAnti-High Mobility Group Protein A1 antibodyAnti-High Mobility Group Protein R antibodyAnti-HMGA1 antibodyAnti-HMGIY antibody |
Information sourced from Uniprot.org