Function | Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels.acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. May play a role in hematopoietic differentiation. |
Protein Name | Hematopoietically-Expressed Homeobox Protein HhexHomeobox Protein HexHomeobox Protein PrhProline-Rich Homeodomain Protein |
Cellular Localisation | NucleusNuclear BodyCytoplasm |
Alternative Antibody Names | Anti-Hematopoietically-Expressed Homeobox Protein Hhex antibodyAnti-Homeobox Protein Hex antibodyAnti-Homeobox Protein Prh antibodyAnti-Proline-Rich Homeodomain Protein antibodyAnti-HHEX antibodyAnti-HEX antibodyAnti-PRH antibodyAnti-PRHX antibody |
Information sourced from Uniprot.org