| Host: | Chicken |
| Applications: | ELISA/ICC/IHC/WB |
| Reactivity: | Drosophila/Guinea Pig/Human/Mouse/Polar Bear/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Chicken monoclonal anti-Recombinant-GFAP (411-422 aa) for use in ELISA, ICC, IHC and WB in Drosophila, Guinea Pig, Human, Mouse, Polar Bear and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | N206A/8 |
| Conjugation: | Unconjugated |
| Isotype: | IgY |
| Formulation: | 1X PBS, 0.05% Sodium Azide pH 7.4 |
| Purification: | Purified by affinity chromatography |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000IHC 1:500ICC 1:500 |
| Storage Instruction: | Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
| Gene Symbol: | GFAP |
| Gene ID: | 2670 |
| Uniprot ID: | GFAP_HUMAN |
| Immunogen Region: | 411-422 aa |
| Specificity: | Cross-reacts with GFAP-R416W and other GFAP mutant proteins. Does not cross-react with other proteins (based on KO validation results). |
| Immunogen: | Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession number P14136) |
| Immunogen Sequence: | Human |
| Tissue Specificity | Expressed in cells lacking fibronectin. |
| Post Translational Modifications | Phosphorylated by PKN1. |
| Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Protein Name | Glial Fibrillary Acidic ProteinGfap |
| Database Links | Reactome: R-HSA-1251985Reactome: R-HSA-9613829 |
| Cellular Localisation | CytoplasmAssociated With Intermediate Filaments |
| Alternative Antibody Names | Anti-Glial Fibrillary Acidic Protein antibodyAnti-Gfap antibodyAnti-GFAP antibody |
Information sourced from Uniprot.org