| Host: | Rabbit |
| Applications: | FC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Recombinant-Glial Cell Line-Derived Neurotrophic Factor for use in FC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | RM1V63 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | FCM: 1:20-1:100 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | GDNF |
| Gene ID: | 2668 |
| Uniprot ID: | GDNF_HUMAN |
| Function | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest. |
| Protein Name | Glial Cell Line-Derived Neurotrophic FactorHgdnfAstrocyte-Derived Trophic FactorAtf |
| Database Links | Reactome: R-HSA-419037Reactome: R-HSA-5673001Reactome: R-HSA-8853659Reactome: R-HSA-9830674 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glial Cell Line-Derived Neurotrophic Factor antibodyAnti-Hgdnf antibodyAnti-Astrocyte-Derived Trophic Factor antibodyAnti-Atf antibodyAnti-GDNF antibody |
Information sourced from Uniprot.org
![Anti-GDNF antibody [3C1] (STJA0002911)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/150177/299868/STJA0002911_1__67443.1633363942.jpg?c=1 "Anti-GDNF antibody [3C1] (STJA0002911)")
