Post Translational Modifications | Phosphorylated. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity. Palmitoylated by ZDHHC3. Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2. |
Function | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
Protein Name | NeuromodulinAxonal Membrane Protein Gap-43Calmodulin-Binding Protein P-57Growth-Associated Protein 43 |
Database Links | Reactome: R-MMU-373760 |
Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionGrowth Cone MembraneSynapseFilopodium MembranePerikaryonDendriteAxonCytoplasmCytoplasmic Surface Of Growth Cone And Synaptic Plasma Membranes |
Alternative Antibody Names | Anti-Neuromodulin antibodyAnti-Axonal Membrane Protein Gap-43 antibodyAnti-Calmodulin-Binding Protein P-57 antibodyAnti-Growth-Associated Protein 43 antibodyAnti-Gap43 antibodyAnti-Basp2 antibody |
Information sourced from Uniprot.org