Anti-Recombinant-FHL2 antibody [RM2F26] (STJA0025495)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Four And A Half Lim Domains Protein 2 for use in IF, IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2F26 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | FHL2 |
| Gene ID | 2274 |
| Uniprot ID | FHL2_HUMAN |
Additional Info
| Function | May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes. |
| Protein Name | Four And A Half Lim Domains Protein 2Fhl-2Lim Domain Protein DralSkeletal Muscle Lim-Protein 3Slim-3 |
| Database Links | Reactome: R-HSA-1989781 |
| Cellular Localisation | CytoplasmNucleusMyofibrilSarcomereZ Line |
| Alternative Antibody Names | Anti-Four And A Half Lim Domains Protein 2 antibodyAnti-Fhl-2 antibodyAnti-Lim Domain Protein Dral antibodyAnti-Skeletal Muscle Lim-Protein 3 antibodyAnti-Slim-3 antibodyAnti-FHL2 antibodyAnti-DRAL antibodyAnti-SLIM3 antibody |
Information sourced from Uniprot.org