Anti-Recombinant-ETAA1 antibody [RM2S47] (STJA0026605)

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STJA0026605
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Ewing s Tumor-Associated antigen 1 is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2S47
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ETAA1
Gene ID: 54465
Uniprot ID: ETAA1_HUMAN
Post Translational Modifications Phosphorylated by ATR.
Function Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets.
Protein Name Ewing's Tumor-Associated Antigen 1
Ewing's Tumor-Associated Antigen 16
Cellular Localisation Nucleus
Localizes At Sites Of Dna Damage Following Replication Stress
Recruited To Stalled Replication Forks Via Interaction With Rpa1 And Rpa2 Subunits Of The Rpa Complex
Alternative Antibody Names Anti-Ewing's Tumor-Associated Antigen 1 antibody
Anti-Ewing's Tumor-Associated Antigen 16 antibody
Anti-ETAA1 antibody
Anti-ETAA16 antibody

Information sourced from Uniprot.org

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