| Function | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
| Protein Name | Steroid Hormone Receptor Err1Estrogen Receptor-Like 1Estrogen-Related Receptor AlphaErr-AlphaNuclear Receptor Subfamily 3 Group B Member 1 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-2151201Reactome: R-HSA-383280Reactome: R-HSA-8939902 |
| Cellular Localisation | NucleusCytoplasmCo-Localizes To The Cytoplasm Only In Presence Of Mapk15 |
| Alternative Antibody Names | Anti-Steroid Hormone Receptor Err1 antibodyAnti-Estrogen Receptor-Like 1 antibodyAnti-Estrogen-Related Receptor Alpha antibodyAnti-Err-Alpha antibodyAnti-Nuclear Receptor Subfamily 3 Group B Member 1 antibodyAnti-ESRRA antibodyAnti-ERR1 antibodyAnti-ESRL1 antibodyAnti-NR3B1 antibody |
Information sourced from Uniprot.org
