Anti-Recombinant-DSC3 antibody [RM2F57] (STJA0025526)

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STJA0025526
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Host: Rabbit
Applications: IF/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Recombinant-Desmocollin-3 for use in IF and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : RM2F57
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: DSC3
Gene ID: 1825
Uniprot ID: DSC3_HUMAN
Function A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and the dermal barrier function. Required for cell-cell adhesion of epithelial cell layers surrounding the telogen hair club, as a result plays an important role in telogen hair shaft anchorage. Essential for successful completion of embryo compaction and embryo development.
Protein Name Desmocollin-3
Cadherin Family Member 3
Desmocollin-4
Ht-Cp
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Cytoplasm
Expressed In The Cytoplasm And At The Cell Membrane Of Oocytes
Alternative Antibody Names Anti-Desmocollin-3 antibody
Anti-Cadherin Family Member 3 antibody
Anti-Desmocollin-4 antibody
Anti-Ht-Cp antibody
Anti-DSC3 antibody
Anti-CDHF3 antibody
Anti-DSC4 antibody

Information sourced from Uniprot.org