Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood. |
Protein Name | Desmocollin-1Cadherin Family Member 1Desmosomal Glycoprotein 2/3Dg2/Dg3 |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
Alternative Antibody Names | Anti-Desmocollin-1 antibodyAnti-Cadherin Family Member 1 antibodyAnti-Desmosomal Glycoprotein 2/3 antibodyAnti-Dg2/Dg3 antibodyAnti-DSC1 antibodyAnti-CDHF1 antibody |
Information sourced from Uniprot.org