Anti-Recombinant-DSC1 antibody [RM2D28] (STJA0025299)

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STJA0025299
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Desmocollin-1 is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2D28
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: DSC1
Gene ID: 1823
Uniprot ID: DSC1_HUMAN
Function A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood.
Protein Name Desmocollin-1
Cadherin Family Member 1
Desmosomal Glycoprotein 2/3
Dg2/Dg3
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Alternative Antibody Names Anti-Desmocollin-1 antibody
Anti-Cadherin Family Member 1 antibody
Anti-Desmosomal Glycoprotein 2/3 antibody
Anti-Dg2/Dg3 antibody
Anti-DSC1 antibody
Anti-CDHF1 antibody

Information sourced from Uniprot.org

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