Host: |
Mouse |
Applications: |
WB/IHC/IF |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Recombinant-Cytokeratin 14 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Monoclonal |
Clone ID: |
SM0705 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
Purification: |
Affinity purification |
Dilution Range: |
WB (H) 1:500-1:1000IHC/IF (H, M, R) 1:500-1:1000 |
Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Gene Symbol: |
Krt14 |
Gene ID: |
16664 |
Uniprot ID: |
K1C14_MOUSE |
Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 14 |
Post Translational Modifications | A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus. Ubiquitinated by the BCR(KLHL24) E3 ubiquitin ligase complex. |
Function | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
Protein Name | Keratin - Type I Cytoskeletal 14Cytokeratin-14Ck-14Keratin-14K14 |
Database Links | Reactome: R-MMU-446107Reactome: -MMU-6805567Reactome: -MMU-6809371 |
Cellular Localisation | CytoplasmNucleusExpressed In Both As A Filamentous Pattern |
Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 14 antibodyAnti-Cytokeratin-14 antibodyAnti-Ck-14 antibodyAnti-Keratin-14 antibodyAnti-K14 antibodyAnti-Krt14 antibodyAnti-Krt1-14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance