Anti-Recombinant-CLDN4/Claudin-4 antibody [RM1D10] (STJA0022905)

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STJA0022905
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Short Description :Rabbit monoclonal anti-Recombinant-Claudin-4 for use in IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IP/WB
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM1D10
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IHC: 1:100-1:200
Formulation:0.01M PBS
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:CLDN4
Gene ID:1364
Uniprot ID:CLD4_HUMAN
Function Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own.
Protein Name Claudin-4
Clostridium Perfringens Enterotoxin Receptor
Cpe-R
Cpe-Receptor
Williams-Beuren Syndrome Chromosomal Region 8 Protein
Database Links Reactome: R-HSA-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Claudin-4 antibody
Anti-Clostridium Perfringens Enterotoxin Receptor antibody
Anti-Cpe-R antibody
Anti-Cpe-Receptor antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 8 Protein antibody
Anti-CLDN4 antibody
Anti-CPER antibody
Anti-CPETR1 antibody
Anti-WBSCR8 antibody

Information sourced from Uniprot.org

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