Anti-Recombinant-Cenexin1/ODF2 antibody [RM2H82] (STJA0025749)

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STJA0025749
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Host: Rabbit
Applications: FC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Outer Dense Fiber Protein 2 is suitable for use in Flow Cytometry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2H82
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ODF2
Gene ID: 4957
Uniprot ID: ODFP2_HUMAN
Post Translational Modifications Tyrosine phosphorylated. Phosphorylated by TSSK4 on Ser-95.
Function Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
Protein Name Outer Dense Fiber Protein 2
Cenexin
Outer Dense Fiber Of Sperm Tails Protein 2
Database Links Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cell Projection
Cilium
Centriole
Spindle Pole
Flagellum
Localized At The Microtubule Organizing Centers In Interphase And Spindle Poles In Mitosis
Localized At The Distal/Subdistal Appendages Of Mother Centrioles
Alternative Antibody Names Anti-Outer Dense Fiber Protein 2 antibody
Anti-Cenexin antibody
Anti-Outer Dense Fiber Of Sperm Tails Protein 2 antibody
Anti-ODF2 antibody

Information sourced from Uniprot.org