Anti-Recombinant-CD108/SEMA7A antibody [RM1F14] (STJA0023107)

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STJA0023107
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Short Description :Rabbit monoclonal anti-Recombinant-Semaphorin-7a for use in IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IP/WB
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM1F14
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IHC: 1:50-1:100
Formulation:0.01M PBS
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:SEMA7A
Gene ID:8482
Uniprot ID:SEM7A_HUMAN
Function Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Protein Name Semaphorin-7a
Cdw108
Jmh Blood Group Antigen
John-Milton-Hargen Human Blood Group Ag
Semaphorin-K1
Sema K1
Semaphorin-L
Sema L
Cd Antigen Cd108
Database Links Reactome: R-HSA-416700
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Extracellular Side
Detected In A Punctate Pattern On The Cell Membrane Of Basal And Supra-Basal Skin Keratinocytes
Alternative Antibody Names Anti-Semaphorin-7a antibody
Anti-Cdw108 antibody
Anti-Jmh Blood Group Antigen antibody
Anti-John-Milton-Hargen Human Blood Group Ag antibody
Anti-Semaphorin-K1 antibody
Anti-Sema K1 antibody
Anti-Semaphorin-L antibody
Anti-Sema L antibody
Anti-Cd Antigen Cd108 antibody
Anti-SEMA7A antibody
Anti-CD108 antibody
Anti-SEMAL antibody

Information sourced from Uniprot.org

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