Anti-Recombinant-CASP9/Caspase 9 antibody [RM1Z26] (STJA0024901)

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STJA0024901
$417.83 - $637.88
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Host: Rabbit
Applications: IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-CASP9/Caspase 9 is suitable for use in Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1Z26
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IP: 1:20
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: Casp9
Gene ID: 12371
Uniprot ID: CASP9_MOUSE
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC.
Protein Name Caspase-9
Casp-9
Apoptotic Protease Mch-6
Apoptotic Protease-Activating Factor 3
Apaf-3
Ice-Like Apoptotic Protease 6
Ice-Lap6 Cleaved Into - Caspase-9 Subunit P35 - Caspase-9 Subunit P10
Database Links Reactome: R-MMU-111458
Reactome: -MMU-111459
Reactome: -MMU-168638
Reactome: -MMU-198323
Reactome: -MMU-418889
Reactome: -MMU-9627069
Alternative Antibody Names Anti-Caspase-9 antibody
Anti-Casp-9 antibody
Anti-Apoptotic Protease Mch-6 antibody
Anti-Apoptotic Protease-Activating Factor 3 antibody
Anti-Apaf-3 antibody
Anti-Ice-Like Apoptotic Protease 6 antibody
Anti-Ice-Lap6 Cleaved Into - Caspase-9 Subunit P35 - Caspase-9 Subunit P10 antibody
Anti-Casp9 antibody
Anti-Mch6 antibody

Information sourced from Uniprot.org