Anti-Recombinant-BRAT1 antibody [RM2P55] (STJA0026316)

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STJA0026316
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Host: Rabbit
Applications: FC/IF/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Brca1-Associated Atm Activator 1 is suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2P55
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: BRAT1
Gene ID: 221927
Uniprot ID: BRAT1_HUMAN
Post Translational Modifications Ubiquitinated by NEDD4, NEDD4L and ITCH.mono- and polyubiquitinated forms are detected.
Function Involved in DNA damage response.activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors.
Protein Name Brca1-Associated Atm Activator 1
Brca1-Associated Protein Required For Atm Activation Protein 1
Cellular Localisation Nucleus
Cytoplasm
Present At Double Strand Breaks (Dsbs)Following Ionizing Radiation Treatment
The Ubiquitinated Form Localizes In The Nucleus In A Ndfip1-Dependent Manner
Alternative Antibody Names Anti-Brca1-Associated Atm Activator 1 antibody
Anti-Brca1-Associated Protein Required For Atm Activation Protein 1 antibody
Anti-BRAT1 antibody
Anti-BAAT1 antibody
Anti-C7orf27 antibody

Information sourced from Uniprot.org