Anti-Recombinant-BAK1 antibody [RM2H17] (STJA0025684)

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STJA0025684
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Host: Rabbit
Applications: IHC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Bcl-2 Homologous Antagonist/Killer is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2H17
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: BAK1
Gene ID: 578
Uniprot ID: BAK_HUMAN
Function Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
Protein Name Bcl-2 Homologous Antagonist/Killer
Apoptosis Regulator Bak
Bcl-2-Like Protein 7
Bcl2-L-7
Database Links Reactome: R-HSA-111452
Reactome: R-HSA-111457
Reactome: R-HSA-5620971
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Bcl-2 Homologous Antagonist/Killer antibody
Anti-Apoptosis Regulator Bak antibody
Anti-Bcl-2-Like Protein 7 antibody
Anti-Bcl2-L-7 antibody
Anti-BAK1 antibody
Anti-BAK antibody
Anti-BCL2L7 antibody
Anti-CDN1 antibody

Information sourced from Uniprot.org

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