| Short Description : | Rabbit monoclonal anti-Recombinant-Atp-Binding Cassette Sub-Family F Member 1 for use in IF, IHC and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | RM2J23 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | ABCF1 |
| Gene ID: | 23 |
| Uniprot ID: | ABCF1_HUMAN |
| Post Translational Modifications | Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. |
| Function | Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. |
| Protein Name | Atp-Binding Cassette Sub-Family F Member 1Atp-Binding Cassette 50Tnf-Alpha-Stimulated Abc Protein |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Isoform 2: CytoplasmNucleusNucleoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family F Member 1 antibodyAnti-Atp-Binding Cassette 50 antibodyAnti-Tnf-Alpha-Stimulated Abc Protein antibodyAnti-ABCF1 antibodyAnti-ABC50 antibody |
Information sourced from Uniprot.org
