| Short Description : | Rabbit polyclonal anti-RAD52 motif-containing protein 1 (118-167 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RDM1 |
| Gene ID: | 201299 |
| Uniprot ID: | RDM1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RDM1 at the amino acid range 118-167 |
| Immunogen Region: | 118-167 aa |
| Specificity: | RDM1 Polyclonal Antibody detects endogenous levels of RDM1 protein. |
| Function | May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. |
| Protein Name | Rad52 Motif-Containing Protein 1Rad52 Homolog B |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmNucleolusIsoform 3 And Isoform 10 Are Predominantly Nuclear And NucleolarAfter Treatment With Proteasomal Inhibitors And Mild Heat-Shock StressIsoform 1Isoform 3Isoform 5Isoform 7Isoform 8 And Isoform 10 Are Relocalized To The Nucleolus As Dot-Like Or Irregular Subnuclear StructuresIsoform 1 Colocalized With Nuclear Promyelocytic Leukemia (Pml) And Cajal Bodies (Cb)This Association With Nuclear Bodies Is Enhanced In Response To Proteotoxic StressBut Not Isoform 1 And Isoform 5Is Relocalized In Nucleolar Caps During Transcriptional ArrestIsoform 1: CytoplasmPml BodyCajal BodyIsoform 1 Is Predominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Rad52 Motif-Containing Protein 1 antibodyAnti-Rad52 Homolog B antibodyAnti-RDM1 antibodyAnti-RAD52B antibody |
Information sourced from Uniprot.org
