| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Rat/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-RDH5 (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave bands at approx 70kDa and 40kDa in Mouse Eye lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the lite |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RDH5 |
| Gene ID: | 5959 |
| Uniprot ID: | RDH5_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002896.2 |
| Immunogen Sequence: | RTPVTNLESLEKT |
| Function | Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner. Has no activity towards all-trans retinal. Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). Also recognizes steroids (androsterone, androstanediol) as its substrates. |
| Protein Name | Retinol Dehydrogenase 5 11-Cis Retinol Dehydrogenase11-Cis Rdh11-Cis Rodh9-Cis Retinol Dehydrogenase9crdhShort Chain Dehydrogenase/Reductase Family 9c Member 5 |
| Database Links | Reactome: R-HSA-2453864Reactome: R-HSA-2453902Reactome: R-HSA-5365859 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLumenal Side |
| Alternative Antibody Names | Anti-Retinol Dehydrogenase 5 antibodyAnti-11-Cis Retinol Dehydrogenase antibodyAnti-11-Cis Rdh antibodyAnti-11-Cis Rodh antibodyAnti-9-Cis Retinol Dehydrogenase antibodyAnti-9crdh antibodyAnti-Short Chain Dehydrogenase/Reductase Family 9c Member 5 antibodyAnti-RDH5 antibodyAnti-HSD17B9 antibodyAnti-RDH1 antibodyAnti-SDR9C5 antibody |
Information sourced from Uniprot.org