Anti-RCE1 antibody (300-350) {Biotin} (STJ502760)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid sequence 300-350 on human RCE1 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-RCE1 (300-350) is suitable for use in ELISA and Western Blot research applications. |
| Applications | ELISA/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.65-0.75 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | RCE1 |
| Gene ID | 9986 |
| Uniprot ID | FACE2_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid sequence 300-350 on human RCE1 protein. |
| Immunogen Region | 300-350 |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Ubiquitinated. Undergoes 'Lys-48'- and 'Lys-63'-linked ubiquitination. 'Lys-48' ubiquitination induces its degradation. Deubiquitinated by USP17L2/USP17 that cleaves 'Lys-63'-linked ubiquitin chains. |
| Function | Protease involved in the processing of a variety of prenylated proteins containing the C-terminal CAAX motif, where C is a cysteine modified with an isoprenoid lipid, A is an aliphatic amino acid and X is any C-terminal amino acid. Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins, leaving the prenylated cysteine as the new C-terminus. Is able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1. |
| Protein Name | Caax Prenyl Protease 2Farnesylated Proteins-Converting Enzyme 2Face-2Prenyl Protein-Specific Endoprotease 2Rce1 HomologHrce1 |
| Database Links | Reactome: R-HSA-5689880Reactome: R-HSA-9648002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Caax Prenyl Protease 2 antibodyAnti-Farnesylated Proteins-Converting Enzyme 2 antibodyAnti-Face-2 antibodyAnti-Prenyl Protein-Specific Endoprotease 2 antibodyAnti-Rce1 Homolog antibodyAnti-Hrce1 antibodyAnti-RCE1 antibodyAnti-FACE2 antibodyAnti-RCE1A antibodyAnti-RCE1B antibody |
Information sourced from Uniprot.org