| Host: | Rabbit |
| Applications: | WB/ICC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-RCAN1/Dscr1 (C-Term) is suitable for use in Western Blot and Immunocytochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000ICC 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RCAN1 |
| Gene ID: | 1827 |
| Uniprot ID: | RCAN1_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | The antibody detects several isoforms of RCAN1 on SDS-PAGE immunoblots of adult mouse muscle and brain, rat PC12 cells, and human A431 and Jurkat cells. The predominate isoforms detected were the 38 kDa RCAN1L and 31 kDa RCAN1S. |
| Immunogen: | RCAN1 (C-terminus) synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminus of human RCAN1. This sequence is highly conserved in rat and mouse RCAN1, and this sequence is found in all four isoforms of RCAN1, but is |
| Post Translational Modifications | Phosphorylation increases its ability to inhibit calcineurin and decreases protein half-life. |
| Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. |
| Protein Name | Calcipressin-1Adapt78Down Syndrome Critical Region Protein 1Myocyte-Enriched Calcineurin-Interacting Protein 1Mcip1Regulator Of Calcineurin 1 |
| Alternative Antibody Names | Anti-Calcipressin-1 antibodyAnti-Adapt78 antibodyAnti-Down Syndrome Critical Region Protein 1 antibodyAnti-Myocyte-Enriched Calcineurin-Interacting Protein 1 antibodyAnti-Mcip1 antibodyAnti-Regulator Of Calcineurin 1 antibodyAnti-RCAN1 antibodyAnti-ADAPT78 antibodyAnti-CSP1 antibodyAnti-DSC1 antibodyAnti-DSCR1 antibody |
Information sourced from Uniprot.org