| Function | Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing. Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules. Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10. Also involved in the alternative splicing of several genes including TJP1. Binds the pre-mRNA (U)GCAUG consensus sequences in downstream intronic regions of alternative exons, regulating their exclusion and inclusion into mRNAs. Independently of its RNA-binding activity, could negatively regulate MAVS by promoting its lysosomal degradation. |
| Protein Name | Rna-Binding Protein 47Rna-Binding Motif Protein 47 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Rna-Binding Protein 47 antibodyAnti-Rna-Binding Motif Protein 47 antibodyAnti-RBM47 antibody |
Information sourced from Uniprot.org
