• Western blot analysis of various lysates, using RASSF2 Rabbit monoclonal antibody (STJ11104103) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-RASSF2 antibody (227-326) [S4103RM] (STJ11104103)

SKU:
STJ11104103

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Ras Association Domain-Containing Protein 2 (227-326) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4103RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RASSF2
Gene ID: 9770
Uniprot ID: RASF2_HUMAN
Immunogen Region: 227-326
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 227-326 of human RASSF2 (P50749).
Immunogen Sequence: HTSGEKQKLKATDYPLIARI LQGPCEQISKVFLMEKDQVE EVTYDVAQYIKFEMPVLKSF IQKLQEEEDREVKKLMRKYT VLRLMIRQRLEEIAETPATI
Tissue Specificity Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Post Translational Modifications Phosphorylated by STK3/MST2 and STK4/MST1.
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Protein Name Ras Association Domain-Containing Protein 2
Cellular Localisation Nucleus
Cytoplasm
Chromosome
Centromere
Kinetochore
Translocates To The Cytoplasm In The Presence Of Stk3/Mst2 And Stk4/Mst1
Alternative Antibody Names Anti-Ras Association Domain-Containing Protein 2 antibody
Anti-RASSF2 antibody
Anti-CENP-34 antibody
Anti-KIAA0168 antibody

Information sourced from Uniprot.org

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