| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ras GTPase-activating protein 1 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RASA1 |
| Gene ID: |
5921 |
| Uniprot ID: |
RASA1_HUMAN |
| Specificity: |
RASA1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | The N-terminus is blocked. Phosphorylated by SRC and LCK. The phosphorylation SRC inhibits its ability to stimulate the Ras-GTPase activity, whereas phosphorylation by LCK does not display any effect on stimulation activity. |
| Function | Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21.this stimulation may be further increased in the presence of NCK1. |
| Protein Name | Ras Gtpase-Activating Protein 1GapGtpase-Activating ProteinRasgapRas P21 Protein ActivatorP120gap |
| Database Links | Reactome: R-HSA-186763Reactome: R-HSA-3928662Reactome: R-HSA-5218921Reactome: R-HSA-5658442Reactome: R-HSA-8849471 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ras Gtpase-Activating Protein 1 antibodyAnti-Gap antibodyAnti-Gtpase-Activating Protein antibodyAnti-Rasgap antibodyAnti-Ras P21 Protein Activator antibodyAnti-P120gap antibodyAnti-RASA1 antibodyAnti-GAP antibodyAnti-RASA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
