| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ras-associated and pleckstrin homology domains-containing protein 1 (370-450 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAPH1 |
| Gene ID: | 65059 |
| Uniprot ID: | RAPH1_HUMAN |
| Immunogen Region: | 370-450 aa |
| Specificity: | RAPH1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 370-450 |
| Function | Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion. |
| Protein Name | Ras-Associated And Pleckstrin Homology Domains-Containing Protein 1 Raph1 Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 18 Protein Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 9 Protein Lamellipodin Proline-Rich Evh1 Ligand 2 Prel-2 Protein Rmo1 |
| Cellular Localisation | Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cell Projection Lamellipodium Filopodium Cytoplasm Cytoskeleton Recruited To The Membrane Via The Ph Domain By The Phosphoinositide Pi(3 4)P2 Colocalizes With Enah/Vasp At The Tips Of Lamellipodia And Filopodia Also Colocalizes With The Pathogens Vaccinia And Enteropathogenic E Coli (Epec) At The Interface Between The Pathogen And Their Actin |
| Alternative Antibody Names | Anti-Ras-Associated And Pleckstrin Homology Domains-Containing Protein 1 antibody Anti-Raph1 antibody Anti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 18 Protein antibody Anti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 9 Protein antibody Anti-Lamellipodin antibody Anti-Proline-Rich Evh1 Ligand 2 antibody Anti-Prel-2 antibody Anti-Protein Rmo1 antibody Anti-RAPH1 antibody Anti-ALS2CR18 antibody Anti-ALS2CR9 antibody Anti-KIAA1681 antibody Anti-LPD antibody Anti-PREL2 antibody Anti-RMO1 antibody |
Information sourced from Uniprot.org