| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-UL-16 binding protein 5 (192-242 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAET1G |
| Gene ID: | 353091 |
| Uniprot ID: | ULBP5_HUMAN |
| Immunogen Region: | 192-242 aa |
| Specificity: | This antibody detects endogenous levels of human RET1G |
| Immunogen: | Synthesized peptide derived from the human RET1G at the amino acid range 192-242 |
| Post Translational Modifications | The functional form is cleaved C-terminally of the GPI-anchor and yields a 28 kDa protein. |
| Function | Isoform 1: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. Isoform 3: Down-regulates the expression of KLRK1 and stimulates natural killer cells to secrete IFNG. Isoform 2: Stimulates natural killer cells to secrete IFNG. |
| Protein Name | Ul-16 Binding Protein 5Retinoic Acid Early Transcript 1g Protein |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorEndoplasmic ReticulumMainly Found IntracellularlyIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Ul-16 Binding Protein 5 antibodyAnti-Retinoic Acid Early Transcript 1g Protein antibodyAnti-RAET1G antibodyAnti-ULBP5 antibody |
Information sourced from Uniprot.org