| Short Description : | Goat polyclonal antibody anti-Radixin (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 80kDa band observed in Human Lymph Node, Tonsil and Spleen lysates (calculated MW of 68.6kDa according to NP_002897.1). The same 80kDa was also observed in lysates of several Mou |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RDX |
| Gene ID: | 5962 |
| Uniprot ID: | RADI_HUMAN |
| Accession Number: | NP_002897.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | QARDETKKTQND |
| Function | Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane. |
| Protein Name | Radixin |
| Database Links | Reactome: R-HSA-437239Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonCleavage FurrowCell ProjectionMicrovillusStereociliumEnriched At The Stereocilium Base With Very Low Levels In The Shaft Of Stereociliary BundlesHighly Concentrated In The Undercoat Of The Cell-To-Cell Adherens Junction And The Cleavage Furrow In The Interphase And Mitotic PhaseRespectively |
| Alternative Antibody Names | Anti-Radixin antibodyAnti-RDX antibody |
Information sourced from Uniprot.org
