| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | RAD52 |
| Gene ID: | 5893 |
| Uniprot ID: | RAD52_HUMAN |
| Immunogen Region: | 125-418 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 125-418 of human Rad52 (NP_602296.2). |
| Immunogen Sequence: | GYGVSEGLKSKALSLEKARK EAVTDGLKRALRSFGNALGN CILDKDYLRSLNKLPRQLPL EVDLTKAKRQDLEPSVEEAR YNSCRPNMALGHPQLQQVTS PSRPSHAVIPADQDCSSRSL SSSAVESEATHQRKLRQKQL QQQFRERMEKQQVRVSTPSA EKSEAAPPAPPVTHSTPVTV SEPLLEKDFLAGVTQELIKT LEDNSEKWAVTPDAGDGVVK PSSRADPAQTSDTLALNNQ |
| Post Translational Modifications | Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR. |
| Function | Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. |
| Protein Name | Dna Repair Protein Rad52 Homolog |
| Database Links | Reactome: R-HSA-3108214Reactome: R-HSA-5685938Reactome: R-HSA-5685939 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Repair Protein Rad52 Homolog antibodyAnti-RAD52 antibody |
Information sourced from Uniprot.org