| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase RAD18 (301-350 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAD18 |
| Gene ID: | 56852 |
| Uniprot ID: | RAD18_HUMAN |
| Immunogen Region: | 301-350 aa |
| Specificity: | Rad18 Polyclonal Antibody detects endogenous levels of Rad18 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RAD18 at the amino acid range 301-350 |
| Protein Name | E3 Ubiquitin-Protein Ligase Rad18Postreplication Repair Protein Rad18Hhr18Hrad18Ring Finger Protein 73Ring-Type E3 Ubiquitin Transferase Rad18 |
| Database Links | Reactome: R-HSA-110314Reactome: R-HSA-8866654 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeAssociates With ChromatinColocalizes With Slf1 In The Nucleus And To CentrosomesRelocalizes With Slf1 To Nuclear Foci In Response To Dna DamageAccumulates With The Slf1-Slf2 And Smc5-Smc6 Complexes At Replication-Coupled Dna Interstrand Repair And Dna Double-Strand Breaks (Dsbs) Sites On Chromatin In A Ubiquitin-Dependent Manner |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rad18 antibodyAnti-Postreplication Repair Protein Rad18 antibodyAnti-Hhr18 antibodyAnti-Hrad18 antibodyAnti-Ring Finger Protein 73 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Rad18 antibodyAnti-RAD18 antibodyAnti-RNF73 antibody |
Information sourced from Uniprot.org