| Short Description : | Rabbit polyclonal RABL3 (1-236) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RABL3 |
| Gene ID: | 285282 |
| Uniprot ID: | RABL3_HUMAN |
| Immunogen Region: | 1-236 |
| Immunogen Sequence: | MASLDRVKVLVLGDSGVGKS SLVHLLCQNQVLGNPSWTVG CSVDVRVHDYKEGTPEEKTY YIELWDVGGSVGSASSVKST RAVFYNSVNGIIFVHDLTNK KSSQNLRRWSLEALNRDLVP TGVLVTNGDYDQEQFADNQI PLLVIGTKLDQIHETKRHEV LTRTAFLAEDFNPEEINLDC TNPRYLAAGSSNAVKLSRFF DKVIEKRYFLREGNQIPGFP DRKRFGAGTLKSLHYD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human RABL3 (NP_776186.2). |
| Function | Required for KRAS signaling regulation and modulation of cell proliferation. Regulator of KRAS prenylation, and probably prenylation of other small GTPases. Required for lymphocyte development and function. Not required for myeloid cell development. |
| Protein Name | Rab-Like Protein 3 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Rab-Like Protein 3 antibodyAnti-RABL3 antibody |
Information sourced from Uniprot.org
