| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Ras-related protein Rab-6C (165-214 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB6C |
| Gene ID: | 84084 |
| Uniprot ID: | RAB6C_HUMAN |
| Immunogen Region: | 165-214 aa |
| Specificity: | Rab 6C Polyclonal Antibody detects endogenous levels of Rab 6C protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RAB6C at the amino acid range 165-214 |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB6C may be involved in the regulation of centrosome duplication and cell cycle progression. |
| Protein Name | Ras-Related Protein Rab-6cRab6-Like Protein Wth3 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-6c antibodyAnti-Rab6-Like Protein Wth3 antibodyAnti-RAB6C antibodyAnti-WTH3 antibody |
Information sourced from Uniprot.org
