| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-RAB5C (160-210) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Rab5c |
| Gene ID: | 19345 |
| Uniprot ID: | RAB5C_MOUSE |
| Immunogen Region: | 160-210 |
| Specificity: | Specific for RAB5C. |
| Immunogen: | A synthetic peptide from aa region 160-210 of mouse RAB5C conjugated to an immunogenic carrier protein has been used as the antigen. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. |
| Protein Name | Ras-Related Protein Rab-5c |
| Database Links | Reactome: R-MMU-432722Reactome: -MMU-6798695Reactome: -MMU-8856828Reactome: -MMU-8873719Reactome: -MMU-8876198 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideEarly Endosome MembraneMelanosome |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-5c antibodyAnti-Rab5c antibody |
Information sourced from Uniprot.org
