• Western blot analysis of various lysates, using RAB4A Rabbit monoclonal antibody (STJ11101978) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-RAB4A antibody (1-100) [S8MR] (STJ11101978)

SKU:
STJ11101978

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-RAB4A (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S8MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB4A
Gene ID: 5867
Uniprot ID: RAB4A_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB4A (P20338).
Immunogen Sequence: MSQTAMSETYDFLFKFLVIG NAGTGKSCLLHQFIEKKFKD DSNHTIGVEFGSKIINVGGK YVKLQIWDTAGQERFRSVTR SYYRGAAGALLVYDITSRET
Post Translational Modifications Phosphorylated by CDK1 kinase during mitosis. Serotonylation of Gln-72 by TGM2 during activation and aggregation of platelets leads to constitutive activation of GTPase activity.
Function Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Involved in protein transport. Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling. Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets.
Protein Name Ras-Related Protein Rab-4a
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-1660499
Reactome: R-HSA-8854214
Reactome: R-HSA-8873719
Reactome: R-HSA-8875656
Cellular Localisation Membrane
Peripheral Membrane Protein
Cytoplasm
Early Endosome Membrane
Recycling Endosome Membrane
Generally Associated With Membranes
Cytoplasmic When Phosphorylated By Cdk1
Alternative Antibody Names Anti-Ras-Related Protein Rab-4a antibody
Anti-RAB4A antibody
Anti-RAB4 antibody

Information sourced from Uniprot.org

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