• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using RAB3GAP2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COS cells, using RAB3GAP2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Rab 3 GAP p150 Polyclonal Antibody

Anti-RAB3GAP2 antibody (417-466 aa) (STJ95292)

SKU:
STJ95292

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Rab3 GTPase-activating protein non-catalytic subunit (417-466 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RAB3GAP2
Gene ID: 25782
Uniprot ID: RBGPR_HUMAN
Immunogen Region: 417-466 aa
Specificity: Rab 3 GAP p150 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p150 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RAB3GAP2 at the amino acid range 417-466
Function Regulatory subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of RAB3GAP1 and RAB3GAP2, which has GTPase-activating protein (GAP) activity towards various Rab3 subfamily members (RAB3A, RAB3B, RAB3C and RAB3D), RAB5A and RAB43, and guanine nucleotide exchange factor (GEF) activity towards RAB18. As part of the Rab3GAP complex, acts as a GAP for Rab3 proteins by converting active RAB3-GTP to the inactive form RAB3-GDP. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. The Rab3GAP complex, acts as a GEF for RAB18 by promoting the conversion of inactive RAB18-GDP to the active form RAB18-GTP. Required for recruiting and activating RAB18 at the endoplasmic reticulum (ER) membrane where it maintains proper ER structure. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Protein Name Rab3 Gtpase-Activating Protein Non-Catalytic Subunit
Rgap-Iso
Rab3 Gtpase-Activating Protein 150 Kda Subunit
Rab3-Gap P150
Rab3-Gap150
Rab3-Gap Regulatory Subunit
Database Links Reactome: R-HSA-6811436
Reactome: R-HSA-8876198
Cellular Localisation Cytoplasm
Endoplasmic Reticulum
In Neurons
It Is Enriched In The Synaptic Soluble Fraction
Alternative Antibody Names Anti-Rab3 Gtpase-Activating Protein Non-Catalytic Subunit antibody
Anti-Rgap-Iso antibody
Anti-Rab3 Gtpase-Activating Protein 150 Kda Subunit antibody
Anti-Rab3-Gap P150 antibody
Anti-Rab3-Gap150 antibody
Anti-Rab3-Gap Regulatory Subunit antibody
Anti-RAB3GAP2 antibody
Anti-KIAA0839 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance