| Post Translational Modifications | Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and CHML. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes. |
| Protein Name | Ras-Related Protein Rab-3d |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-3d antibodyAnti-RAB3D antibodyAnti-GOV antibodyAnti-RAB16 antibody |
Information sourced from Uniprot.org