Anti-RAB33A antibody (118-237) (STJ11102839)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RAB33A (118-237) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAB33A |
| Gene ID | 9363 |
| Uniprot ID | RB33A_HUMAN |
| Immunogen Region | 118-237 |
| Immunogen Sequence | DVTKMTSFTNLKMWIQECNG HAVPPLVPKVLVGNKCDLRE QIQVPSNLALKFADAHNMLL FETSAKDPKESQNVESIFMC LACRLKAQKSLLYRDAERQQ GKVQKLEFPQEANSKTSCPC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 118-237 of human RAB33A (NP_004785.1). |
Additional Info
| Tissue Specificity | Expressed only in lymphoid cell lines. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Modulates autophagosome formation through interaction with ATG16L1. |
| Protein Name | Ras-Related Protein Rab-33aSmall Gtp-Binding Protein S10 |
| Database Links | Reactome: R-HSA-8854214Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-33a antibodyAnti-Small Gtp-Binding Protein S10 antibodyAnti-RAB33A antibodyAnti-RABS10 antibody |
Information sourced from Uniprot.org