Anti-RAB27B antibody (1-218) (STJ112425)

Name: Anti-RAB27B antibody (1-218) (STJ112425)
SKU: STJ112425
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ112425

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Short Description	Rabbit polyclonal RAB27B (1-218) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	RAB27B
Gene ID	5874
Uniprot ID	RB27B_HUMAN
Immunogen Region	1-218
Immunogen Sequence	MTDGDYDYLIKLLALGDSGV GKTTFLYRYTDNKFNPKFIT TVGIDFREKRVVYNAQGPNG SSGKAFKVHLQLWDTAGQER FRSLTTAFFRDAMGFLLMFD LTSQQSFLNVRNWMSQLQAN AYCENPDIVLIGNKADLPDQ REVNERQARELADKYGIPYF ETSAATGQNVEKAVETLLDL IMKRMEQCVEKTQIPDTVNG GNSGNLDGEKPPEKKCIC
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2).

Tissue Specificity	Expressed primarily in testis.
Function	Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes.
Protein Name	Ras-Related Protein Rab-27b C25kg
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-8873719 Reactome: R-HSA-8876198
Cellular Localisation	Membrane Lipid-Anchor Late Endosome
Alternative Antibody Names	Anti-Ras-Related Protein Rab-27b antibody Anti-C25kg antibody Anti-RAB27B antibody

Information sourced from Uniprot.org