| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB20 |
| Gene ID: | 55647 |
| Uniprot ID: | RAB20_HUMAN |
| Immunogen Region: | 80-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-190 of human RAB20 (NP_060287.1). |
| Immunogen Sequence: | YDVNHRQSLVELEDRFLGLT DTASKDCLFAIVGNKVDLTE EGALAGQEKEECSPNMDAGD RVSPRAPKQVQLEDAVALYK KILKYKMLDEQDVPAAEQMC FETSAKTGYNV |
| Tissue Specificity | Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level). |
| Function | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. |
| Protein Name | Ras-Related Protein Rab-20 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesiclePhagosomePhagosome MembraneLipid-AnchorCytoplasmic SideHighly Enriched On Apical Endocytic Structures In Polarized Epithelial Cells Of Kidney Proximal TubulesRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-20 antibodyAnti-RAB20 antibody |
Information sourced from Uniprot.org