| Short Description : | Goat polyclonal RAB15, member RAS oncogene family (115aa C-Term) antibody for use in WB in human, mouse, rat, bovine, canine, chicken, avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep and simian samples. Datasheet inclu |
| Applications: | WB |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 4 mg/mL |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Dilution Range: | WB 1:250-1:2000 |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Gene Symbol: | RAB15 |
| Gene ID: | 376267 |
| Uniprot ID: | RAB15_HUMAN |
| Accession Number: | ENSG00000139998 |
| Immunogen: | Purified recombinant peptide derived from within residues 115 aa to the C-terminus of mouse Rab15 produced in E. coli. |
| Immunogen Region: | 115aa C-Term |
| Immunogen Sequence: | MGVQKILIGNKADEEQKRQV GVQKILIGNKADEEQKRQVG VQKILIGNKADEEQKRQVGR QKILIGNKADEEQKRQVGRE KILIGNKADEEQKRQVGREQ ILIGNKADEEQKRQVGREQG |
| Specificity: | In transfected cells detects Rab15 by Western blot. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB15 may act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal. |
| Protein Name | Ras-Related Protein Rab-15 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-15 antibodyAnti-RAB15 antibody |
Information sourced from Uniprot.org
