Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Ras-related protein Rab-12 (186-236 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RAB12 |
Gene ID: |
201475 |
Uniprot ID: |
RAB12_HUMAN |
Immunogen Region: |
186-236 aa |
Specificity: |
This antibody detects endogenous levels of RAB12 at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human RAB12 at the amino acid range 186-236 |
Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy. |
Protein Name | Ras-Related Protein Rab-12 |
Database Links | Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
Cellular Localisation | Recycling Endosome MembraneLipid-AnchorCytoplasmic SideLysosome MembraneGolgi Apparatus MembraneCytoplasmic VesicleAutophagosome |
Alternative Antibody Names | Anti-Ras-Related Protein Rab-12 antibodyAnti-RAB12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance