| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB11FIP1 |
| Gene ID: | 80223 |
| Uniprot ID: | RFIP1_HUMAN |
| Immunogen Region: | 330-540 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 330-540 of human RAB11FIP1 (NP_079427.4). |
| Immunogen Sequence: | EAKGEIKDSSPSSSPSPKGF RKKHLFSSTENLAAGSWKEP AEGGGLSSDRQLSESSTKDS LKSMTLPSYRPAPLVSGDLR ENMAPANSEATKEAKESKKP ESRRSSLLSLMTGKKDVAKG SEGENPLTVPGREKEGMLMG VKPGEDASGPAEDLVRRSEK DTAAVVSRQGSSLNLFEDVQ ITEPEAEPESKSEPRPPISS PRAPQTRAVKP |
| Tissue Specificity | Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine. |
| Function | A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. Interaction with RAB14 may function in the process of neurite formation. |
| Protein Name | Rab11 Family-Interacting Protein 1Rab11-Fip1Rab-Coupling Protein |
| Database Links | |
| Cellular Localisation | Recycling EndosomeCytoplasmic VesicleRab11a Rather Than Rab4a Mediates Localization In The Endocytic Recycling Compartment (Erc)Colocalizes With Rab11 And Rab14 On Punctate VesiclesIsoform 2: Cytoplasmic VesiclePhagosome MembraneMembrane-Bound (Isoform 2)Colocalizes With Rab11a At Phagosomes (Isoform 2) |
| Alternative Antibody Names | Anti-Rab11 Family-Interacting Protein 1 antibodyAnti-Rab11-Fip1 antibodyAnti-Rab-Coupling Protein antibodyAnti-RAB11FIP1 antibodyAnti-RCP antibody |
Information sourced from Uniprot.org
