Host: |
Rabbit |
Applications: |
IF/ICC/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Monoclonal |
Clone ID: |
SRM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
RGS9BP |
Gene ID: |
388531 |
Uniprot ID: |
R9BP_HUMAN |
Immunogen Region: |
1-107 aa |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human R9AP/RGS9BP (NP_997274.2). |
Immunogen Sequence: |
MAREECKALLDGLNKTTACY HHLVLTVGGSADSQNLRQEL QKTRQKAQELAVSTCARLTA VLRDRGLAADERAEFERLWV AFSGCLDLLEADMRRALELG AAFPLHA |
Function | Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation. |
Protein Name | Regulator Of G-Protein Signaling 9-Binding ProteinRgs9-Anchoring Protein |
Database Links | Reactome: R-HSA-2514859 |
Cellular Localisation | MembraneSingle-Pass Type Iv Membrane Protein |
Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 9-Binding Protein antibodyAnti-Rgs9-Anchoring Protein antibodyAnti-RGS9BP antibodyAnti-R9AP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance