Anti-QSOX2 antibody (370-650) (STJ117408)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal QSOX2 (370-650) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | QSOX2 |
| Gene ID | 169714 |
| Uniprot ID | QSOX2_HUMAN |
| Immunogen Region | 370-650 |
| Immunogen Sequence | VKKLLEMLQEWLASLPLDRI PYNAVLDLVNNKMRISGIFL TNHIKWVGCQGSRSELRGYP CSLWKLFHTLTVEASTHPDA LVGTGFEDDPQAVLQTMRRY VHTFFGCKECGEHFEEMAKE SMDSVKTPDQAILWLWKKHN MVNGRLAGHLSEDPRFPKLQ WPTPDLCPACHEEIKGLASW DEGHVLTFLKQHYGRDNLLD TYSADQGDSSEGGTLARGEE EEKRLTPPEVSHGDRDTQS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 370-650 of human QSOX2 (NP_859052.3). |
Additional Info
| Tissue Specificity | Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles. |
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. |
| Protein Name | Sulfhydryl Oxidase 2Neuroblastoma-Derived Sulfhydryl OxidaseQuiescin Q6-Like Protein 1 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinSecretedCell MembraneNucleus MembraneSeems To Be Predominantly Targeted To The Nuclear And Outer Plasma Membrane |
| Alternative Antibody Names | Anti-Sulfhydryl Oxidase 2 antibodyAnti-Neuroblastoma-Derived Sulfhydryl Oxidase antibodyAnti-Quiescin Q6-Like Protein 1 antibodyAnti-QSOX2 antibodyAnti-QSCN6L1 antibodyAnti-SOXN antibody |
Information sourced from Uniprot.org