Anti-QSOX1 antibody (500-550) (STJ502741)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 500-550 on human QSOX1 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-QSOX1 (500-550) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.55-0.75 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | QSOX1 |
| Gene ID | 5768 |
| Uniprot ID | QSOX1_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 500-550 on human QSOX1 protein. |
| Immunogen Region | 500-550 |
Additional Info
| Tissue Specificity | Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. |
| Post Translational Modifications | N-glycosylated. O-glycosylated on Thr and Ser residues. |
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. |
| Protein Name | Sulfhydryl Oxidase 1HqsoxQuiescin Q6 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Membrane ProteinSecretedA Small Proportion Is SecretedProbably Via A Proteolytic Cleavage That Removes The Membrane AnchorIsoform 2: SecretedFound In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells |
| Alternative Antibody Names | Anti-Sulfhydryl Oxidase 1 antibodyAnti-Hqsox antibodyAnti-Quiescin Q6 antibodyAnti-QSOX1 antibodyAnti-QSCN6 antibodyAnti-UNQ2520 antibodyAnti-PRO6013 antibody |
Information sourced from Uniprot.org