| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PZP (620-740) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PZPUniprot ID=PZP_HUMAN" |
| Immunogen Region: |
620-740 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 620-740 of human PZP (NP_002855.2). |
| Immunogen Sequence: |
VKDLTNFPDNVDQQEEEQGH CPRPFFIHNGAIYVPLSSNE ADIYSFLKGMGLKVFTNSKI RKPKSCSVIPSVSAGAVGQG YYGAGLGVVERPYVPQLGTY NVIPLNNEQSSGPVPETVRS Y |
| Tissue Specificity | Plasma. Prominent constituent of late-pregnancy sera. |
| Function | Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. |
| Protein Name | Pregnancy Zone ProteinC3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 6 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Pregnancy Zone Protein antibodyAnti-C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 6 antibodyAnti-PZP antibodyAnti-CPAMD6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
