Anti-PZP antibody (1301-1350 aa) (STJ192551)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1301-1350
General Information
| Short Description | Rabbit polyclonal anti-Pregnancy zone protein (1301-1350 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PZP |
| Gene ID | 5858 |
| Uniprot ID | PZP_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1301-1350 |
| Immunogen Region | 1301-1350 aa |
| Specificity | PZP Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. |
| Protein Name | Pregnancy Zone ProteinC3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 6 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Pregnancy Zone Protein antibodyAnti-C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 6 antibodyAnti-PZP antibodyAnti-CPAMD6 antibody |
Information sourced from Uniprot.org